butabarbital will lower the extent or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.diazepam will increase the degree or outcome of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. If coadministration of lonafarnib (a delicate CYP3A